This presentation will focus on recent Janssen plans for the application of an S88 recipe based approach, encompassing an end to end execution model, from the laboratories, through clinical manufacturing, into commercial production. The S88 standard is used as a model for defining the process content, the execution, and the visualization of the resultant data. We have an extensive installed base of OSI Pi across our network, and it is viewed as the link between process execution/data collection and visualization/analytics, bringing forward the full context of the data. Recent examples from our clinical and commercial manufacturing sites will be reviewed.